Sexual stage development of cryptosporidia in the Caco-2 cell line

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Sexual stage development of cryptosporidia in the Caco-2 cell line.

We used the spontaneously differentiated human intestinal epithelial cell line Caco-2 to develop an in vitro model of Cryptosporidium sp. infection. The mean cell infection rate was 3% +/- 2%. Asexual stages of cryptosporidia were observed on day 2 postinoculation. Transmission electron microscopy showed the presence of macrogametes at day 5. This cell line appears to be suited to the study of ...

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ژورنال

عنوان ژورنال: Infection and Immunity

سال: 1991

ISSN: 0019-9567,1098-5522

DOI: 10.1128/iai.59.12.4610-4613.1991